From California to Pennsylvania, governors and mayors across the U.S. are ratcheting up COVID-19 restrictions amid the record-shattering resurgence of the virus that is all but certain to get worse because of holiday travel and family gatherings over Thanksgiving. Leaders are closing businesses or curtailing hours and other operations, and they are ordering or imploring people to stay home and keep their distance from others to help stem a rising tide of infections that threatens to overwhelm the health care system.